A quiet afternoon at Marlinspike Hall is shattered by a news report, a startling broadcast from the distant, tumultuous land of San Theodoros. The headlines scream of betrayal and conspiracy: the beloved opera diva Bianca Castafiore, along with her entourage and even the intrepid detectives Thomson and Thompson, have been imprisoned, accused of plotting to overthrow the iron-fisted regime of General Tapioca. Worse still, the broadcast implicates Tintin, Captain Haddock, and Professor Calculus as the masterminds behind this alleged coup, a claim they vehemently deny.
Captain Haddock, initially finding a grim amusement in Castafiore's predicament, soon finds his joviality replaced by a righteous fury at the baseless accusations. Despite Tintin's deep-seated suspicion that this entire affair is a cleverly laid trap, Haddock and Professor Calculus, driven by loyalty and a desire to clear their names, resolve to travel to San Theodoros. Tintin, ever the protector of his friends, reluctantly follows, his faithful Snowy by his side, sensing the looming danger.
Upon their arrival in the vibrant, yet volatile, South American nation, Haddock and Calculus are swiftly whisked away to a secluded country estate, ostensibly for their comfort, but which soon reveals itself to be a gilded cage. Tintin, with his keen reporter's instincts, uncovers the insidious truth: the entire elaborate conspiracy, from Castafiore's imprisonment to their own implication, is the handiwork of their old adversary, Colonel Sponsz. This Bordurian operative, seeking revenge for past humiliations, has orchestrated the plot with General Tapioca's full cooperation.
A chance encounter with Pablo, a familiar face from a previous adventure, provides Tintin with a lifeline. With Pablo's aid, Tintin, Snowy, Haddock, and Calculus manage a daring escape from their captors, finding refuge deep within the jungle. There, amidst the dense foliage, they reunite with their old friend, General Alcazar, who now leads a ragtag band of anti-Tapioca guerrillas known as the Picaros. However, Alcazar's revolutionary aspirations are severely hampered by the Picaros' debilitating alcoholism, a condition exacerbated by Tapioca's cunning strategy of dropping cases of whiskey near their camp.
Professor Calculus, ever the genius, unveils a remarkable invention: a pill that renders the taste of alcohol utterly repulsive. He demonstrates its effectiveness on a bewildered Captain Haddock, who suddenly finds his beloved whiskey an unbearable torment. Tintin, seizing this opportunity, strikes a deal with Alcazar: he will cure the Picaros of their addiction, but only if Alcazar promises a bloodless revolution. Meanwhile, the flamboyant musical troupe, the "Jolly Follies," led by the irrepressible Jolyon Wagg, inadvertently stumbles into the Picaros' camp, having lost their way to Tapiocapolis.
As the carnival festivities engulf Tapiocapolis, a plan begins to coalesce. The now-sober Picaros, disguised in the vibrant costumes of the Jolly Follies, infiltrate the city under the cover of the revelry. They storm the presidential palace, a swift and bloodless coup unfolding amidst the joyous chaos. Thomson and Thompson are dramatically rescued moments before facing a firing squad, while Castafiore and her assistants are freed from their prison cells.
With Tapioca and Sponsz exiled, General Alcazar is reinstated as president. Yet, as Tintin, Snowy, Haddock, and Calculus prepare for their return journey to Marlinspike Hall, a lingering sense of the cyclical nature of power hangs in the air. The slums of Tapiocapolis remain, their inhabitants still in squalor, suggesting that while the faces of power may change, the underlying struggles often endure.